15 Aug Protein Annotation Assignment
- PLEASE USE INSTUCTIONS AND PDF I HAVE ATTACHED TO WRITE PAPER
- exploit knowledge of the fundamental principles of molecular biology to analyze contributions of DNA and proteins to human physiologynd behavior
- identify, select, and query the appropriate database to best answer the bioinformatics question at hand, and effectively and accurately interpret the outcome
For the protein annotation project, you will use the protein coded by the gene in the gene annotation project, if it was noncoding gene, choose any protein of interest to annotate. The following tasks must be completed and must provide screenshots
- Provide the protein sequence from the provided gene sequence and state protein name, gene name and amino acid length. Include accession ID or protein ID from UniProt, or NCBI
- identify the protein function
- protein family, conserved domains: name and location by amino acid number
- gene ontology (GO): Provide 2 GOs per each one of these sections where available. Sections: Molecular function, Biological process and cellar component. Include GO ID, name, and definition
- computational analysis of protein-protein interactions: total number of interactors and at least three names and protein ids of the interactors where available, if there is none, choose 3 other unique features of your protein not on the list
Do not cut and paste your database results to report your findings. Write two to three paragraphs reporting the information you have obtained about this protein. Imagine this is a report you will present to an employer or a group of researchers interested in this protein.
|
Content |
Excellent |
Very Good |
Good |
Fair |
Poor |
|
Points |
4 |
3 |
2 |
1 |
0 |
|
Protein Identification |
correct identification of protein name, gene name, sequence, protein id and amino acid length |
correctly identifies at least three of the listed features |
correctly identifies at least two of the listed features. |
Wrong identification of all the listed features |
no answer |
|
Protein Function |
All functions |
most functions |
Some functions |
Wrong protein function identification |
no answer |
|
Family and Domain information |
Correct protein family, conserved domain names, amino acid location |
Correctly identifies two of the three required features |
Correctly identifies one of the required three features |
Wrong identification for all |
no answer |
|
Gene ontology information |
Have correct six GO terms in three sections including id name and definition |
Have correct six Go terms in the three sections but is missing the required description |
Have no fewer than three correct GO terms with some description |
Have fewer than three correct GO terms |
no answer |
|
Protein protein interactions |
Correctly Identifies all the three interactors with protein names and ids |
Correctly identifies fewer three interactors but has the names and protein ids |
Correctly identifies all the three interactors with missing names and ids |
Identifies fewer than three interactors with no names and ids |
Use this link to find information about the protein and provide the amino acid sequence:
