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Increasing compliance and/or being able to accurately detect whether a drug was taken or not

Increasing compliance and/or being able to accurately detect whether a drug was taken or not, as opposed to subject reporting, could improve the quality of the data and adherence by subjects. Do you think this is an appropriate tool to improve quality in clinical trials? Yes or No. Explain and provided examples & reference your work to support. Provide pros and cons? What about research ethics

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